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This cream is used for acne, dry, rough patches and tiny bumps on skin. Tretinoin is a me dicine that is used for the treatment of acne vulgaris tretinoin is a me dicine that is used for the treatment of acne vulgaris; an skin disorder that is known as common acne and that is caused by hair follicles that become plugged with oil and dead skin cells causing blackheads, whiteheads, or pimples. This cream is used for acne, dry, rough patches and tiny bumps on skin.